55. A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance. Randall T. Mertens, Aditya Misra, Peng Xiao, Seungbyn Baek, Joseph M. Rone, Davide Mangani, Kisha N. Sivanathan, Adedamola S. Arojojoye, Samuel G. Awuah, Insuk Lee, Guo-Ping Shi, Boryana Petrova, Jeannette R. Brook, Ana C. Anderson, Richard A. Flavell, Naama Kanarek, Martin Hemberg, Roni Nowarski, Immunity, 2024, ISSN 1074-7613, https://doi.org/10.1016/j.immuni.2024.06.001.
|
54. Enhanced mucosal mitochondrial function corrects dysbiosis and OXPHOS metabolism in IBD. Neeraj Kapur, M. Ashfaqul Alam, Syed Adeel Hassan, Parth H Patel, Lesley A. Wempe, Sarayu Bhogoju, Tatiana Goretsky, Jong Hyun Kim, Jeremy Herzog, Yong Ge, Samuel G. Awuah, Mariana Byndloss, Andreas J Baumler, Mansour M. Zadeh, R. Balfour Sartor, Terrence Barrett bioRxiv 2024.03.14.584471; doi: https://doi.org/10.1101/2024.03.14.584471
|
50. Arojojoye, A. S., Walker, B., Dawahare, J. C., Afrifa, M. O. A, Parkin, S., Awuah, S. G.* Circumventing physicochemical barriers of cyclometalated gold(III) dithiocarbamate complexes with protein-based nanoparticle delivery to enhance anticancer activity. ACS Appl. Mater. Interfaces 2023, 15, 37, 43607–43620
|
38. Marloye, M.; Haider, I.; Moore, C. J.; Mertens, R. T.; Ingels, A.; Koch, M.; Nowicki, M. O.; Mathieu, V.; Pritchard, J.; Awuah, S. G.; Lawler, S. E.; Meyer, F.; Dufrasne, F.; Berger, G., Self-assembled ruthenium and osmium nanosystems display a potent anticancer profile by interfering with metabolic activity. Inorganic Chemistry Frontiers 2022, in press
|
Prior to The University of Kentucky:
16. Maximizing synergistic activity when combining RNAi and platinum-based anticancer agents. Haihua Xiao, Ruogu Qi, Ting Li, Samuel G. Awuah, Yaorong Zheng, Wei Wei, Xiang Kang, Haiqin Song, Yongheng Wang, Yingjie Yu, Molly A. Bird, Xiabin Jing, Michael B. Yaffe, Michael J. Birrer, and P. Peter Ghoroghchian J. Am. Chem. Soc. , ASAP, A-L (2017).
15. Repair shielding of platinum-DNA lesions in testicular germ cell tumors by high-mobility group box protein 4 imparts cisplatin hypersensitivity . Samuel G. Awuah, Imogen Riddell, and Stephen J. Lippard, PNAS, 5, 950-955 (2017).
14. Chemical approach to positional isomers of glucose-platinum conjugates: specific cancer targeting through glucose-transporter mediated uptake in vitro and in vivo . Malay Patra, Samuel G. Awuah, and Stephen J. Lippard, J. Am. Chem. Soc. , 138, 12541-12551 (2016).
13. Tobacco mosaic virus delivery of phenanthriplatin for cancer therapy . Anna E. Czapar, Yao-Rong Zheng, Imogen Riddell, Sourabh Shukla, Samuel G. Awuah, Stephen J. Lippard, and Nicole F. Steinmetz ACS Nano , 10, 4119-4126 (2016).
12. A Platinum(IV) Prodrug Preferentially Targets IDO Providing Enhanced Ovarian Cancer Immuno-Chemotherapy . Samuel G. Awuah, Yao-Rong Zheng, Peter M. Bruno, Michael T. Hemann, and Stephen J. Lippard, J. Am. Chem. Soc. , 137, 14854-14857 (2015).
11. Selective accumulation and specific tumor damage by folate receptor-targeted CA-4 prodrug as part of a combination of photodynamic therapy and site-specific chemotherapy . Gregory Nkepang, Moses Bio, Pallavi Rajaputra, Samuel G. Awuah, and Youngjae You, Cancer Res. , 75, 4394 (2015).
10. Necroptosis-Inducing Rhenium(V) Oxo Complexes . Kogularamanan Suntharalingam, Samuel G. Awuah, Peter M. Bruno, Timothy C. Johnstone, Fang Wang, Wei Lin, Yao-Rong Zheng, Julia E. Page, Michael T. Hemann and Stephen J. Lippard, J. Am. Chem. Soc. , 137, 2967-2974 (2015).
9. Dual functioning thieno-pyrrole fused BODIPY dyes for NIR optical imaging and photodynamic therapy – singlet oxygen generation without heavy halogen atom assistance. Ryan L. Watley, Samuel G. Awuah, Moses Bio, Robert Cantu, Habtom B. Gobeze, Vladimir N. Nesterov, Sushanta K. Das, Francis D'Souza, and Youngjae You, Chem. As. J. , 10, 1335-1343 (2015).
8. Folate receptor-mediated enhanced and specific delivery of far-red light-activatable prodrugs of Combretastatin A-4 to FR-positive tumor. Gregory Nkepang, Moses Bio, Pallavi Rajaputra, Samuel G. Awuah, and Youngjae You, Bioconjugate Chem. , 25, 2175-2188 (2014).
7. Thieno-pyrrole-Fused 4,4-Difluoro-4-bora-3a,4a-diaza- s-indacenes Fullerene Dyads: Utilization of Near-Infrared Sensitizers for Ultrafast Charge Separation in Donor- Acceptor Systems. Venugopal Bandi, Sushanta K. Das, Samuel G. Awuah, Youngjae You, and Francis D'Souza, J. Am.Chem. Soc., 136, 7571-7574 (2014).
6. Thieno-pyrrole Fused BODIPY Intermediate as a Versatile Platform to Multi-functional NIR Agents. Samuel G. Awuah, Sushanta K. Das, Francis D'Souza, and Youngjae You, Chem. As. J., 8, 3123-3132 (2013).
5. Site-Specific and Far-Red-Light-Activatable Prodrug of Combretastatin A-4 Using Photo-Unclick Chemistry. Moses Bio, Pallavi Rajaputra, Gregory Nkepang, Samuel G. Awuah, Abugafar M. L. Hossion, and Youngjae You, J. Med. Chem., 56, 3969-3942 (2013).
4. Visible light controlled release of anticancer drug through double activation of pro-drug. Abugafar M. L. Hossion, Moses Bio, Gregory Nkepang, Samuel G. Awuah, and Youngjae You, ACS Med. Chem. Lett., 4, 124-127 (2013).
3. Boron Dipyrromethene (BODIPY)-Based Photosensitizers for Photodynamic Therapy. Samuel G. Awuah, and Youngjae You, RSC. Adv., 2, 11169-11183 (2012).
2. New Pyran dyes for Dye-Sensitized Solar Cells. Samuel G. Awuah, Jason Polreis, Joshi Prakash, Qiquan Qiao, and Youngjae You, Photochem. Photobiol. A., 224, 116-122 (2011).
1. Singlet Oxygen Generation by Novel NIR BODIPY Dyes. Samuel G. Awuah, Jason Polreis, Vidya Biradar, and Youngjae You, Org. Lett., 13, 3884-3887 (2011).